HORDB

ID: hor002358
Uniprot ID: P15513??53-60)
Protein name: Myomodulin-B
Gene name: MYOMOD1
Organism: Aplysia californica (California sea hare)
Family: Myomodulin family
Source: animal
Expression: Expressed in all ganglia of the CNS, but only in a subset of neurons including L10 in the abdominal ganglion and B16 in the buccal ganglion.
Disease: NA
Comments: NA
Taxonomy: Aplysia (genus), Aplysiidae (family), Aplysioidea (superfamily), Aplysiida (order), Tectipleura, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: GSYRMMRL
Length: 8(53-60)
Propeptide: MQVYMLLPLAVFASLTYQGACEETAAAQTSSDASTSSASSEHAENELSRAKRGSYRMMRLGRGLHMLRLGKRGGPVEPESEENLETLLNLLQGYYSDVPEYPSEFDDTDLAYPYEEYDAPAHPRYRRSTPPTDGVVAPDVLQKGSSEFEDFGDSQLDESDEGYYGYDPENYLYGDFEDYLEPEEGGLGEEKRSLSMLRLGKRGLSMLRLGKREGEEGDEMDKKQDESLNDDFENDDIKRTLSMLRLGKRPMSMLR
Signal peptide: MQVYMLLPLAVFASLTYQ
Modification: T8 Leucine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002358_AF2.pdb

hor002358_ESM.pdb

Mass:	113827	Formula:	C42H72N14O11S2
Absent amino acids:	ACDEFHIKNPQTVW	Common amino acids:	MR
pI:	11.15	Basic residues:	2
Polar residues:	3	Hydrophobic residues:	1
Hydrophobicity:	-48.75	Boman Index:	-2282
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	48.75
Instability Index:	-2541.25	Extinction Coefficient cystines:	1490
Absorbance 280nm:	212.86

PubMed ID: 1788132
Title: Structure, Bioactivity, and Cellular Localization of Myomodulin B: A Novel Aplysia Peptide